Devin × Natty Vision
From Fat Back to Fit — My Ascension Protocol
I used to be in the best shape of my life. Then I let it slip. This is my ascension protocol — the exact compounds I'm running to climb back. Doses, timing, what I'm noticing as it unfolds.
Research & educational use only. These compounds are research chemicals. Nothing here is medical advice and should not inform personal health decisions. Consult a licensed physician before using any of these compounds. My results are my own.
The Compounds
GLP-1 / GIP / Glucagon Triple Agonist
Role
Foundation of the whole protocol. Fat coming off consistently, appetite well managed.
Timing
Once a week, subcutaneous. Same day every week for consistency.
Why 2 mg: Worked up to this dose carefully. At 2 mg I'm getting strong fat loss, better insulin sensitivity, and proper appetite control without the GI issues that come from pushing too aggressively. The titration matters.
Mitochondrial-Derived Peptide
Role
Mitochondrial support and metabolic flexibility. Pairs well with Retatrutide — both push fat oxidation from different angles.
Timing
Daily, subcutaneous. Lower daily dose for more consistent levels.
Synergy with Reta: Running MOTS-c alongside Retatrutide means hitting fat oxidation from a GLP-1 angle and a mitochondrial angle simultaneously. The combination feels significantly more effective than either alone.
Body Protective Compound
Role
Joints taking a beating as training volume ramps up. BPC keeps everything feeling manageable. No major flare-ups.
Timing
Split into two shots per day, morning and evening, subcutaneous.
Paired with TB-500: BPC handles local tissue repair while TB-500 covers the bigger picture systemically. Together they keep the body recovering fast enough to keep training hard.
Thymosin Beta-4 Fragment
Role
Systemic recovery anchor. Reduces inflammation and keeps connective tissue healthy as training volume climbs.
Timing
Once or twice per week, subcutaneous. Adjusted within the range depending on training load.
Recovery stack: The BPC and TB-500 combination is well-documented in research circles for a reason. For anyone pushing training volume hard, running both simultaneously is worth the extra effort.
ERR Agonist / Exercise Mimetic
Role
Activates the same mitochondrial pathways as endurance training. Keeps fat oxidation elevated on lighter training days.
Timing
Daily, subcutaneous. Consistent dosing keeps pathway activation steady.
Why include it: For a recomp protocol while in a caloric deficit, having an exercise mimetic running feels like the right insurance policy. The mechanism is well-understood even if the compound is newer.
Copper Peptide
Role
Protecting skin and connective tissue. When you lean out fast, your skin takes a hit. GHK-Cu helps a lot with that.
Timing
Daily, subcutaneous. Dose on the lower end since other stuff is running.
What I'm noticing: Skin is holding up way better than expected at this rate of fat loss. Recovery feels cleaner too. This one flies under the radar but I wouldn't cut it from the stack.
Nicotinamide Adenine Dinucleotide
Role
Cellular energy production and longevity signalling. Pairs naturally with MOTS-c — both operate through mitochondrial pathways.
Timing
Daily, subcutaneous. Bioavailability through subq is significantly better than other delivery methods.
Energy and recovery: The combination of NAD+ and MOTS-c is creating a noticeable baseline energy uplift that makes high-volume training feel more sustainable. Sleep quality has also improved.
Master Antioxidant
Role
Running this many compounds puts oxidative stress on the body. Glutathione is my antioxidant anchor — keeps inflammation in check and supports liver health.
Timing
Daily, subcutaneous. Injecting bypasses absorption issues, so the dose stays lower while still hitting effectively.
Liver and inflammation: Often overlooked in peptide stacks but it shouldn't be. The detox support and anti-inflammatory effects are keeping bloodwork looking clean. Worth the addition.
How It's Going
Early Phase
Getting Started
Brought all 8 compounds online together. The opening stretch is mostly about letting things settle. Appetite is regulating fast and energy is stabilising.
Build Phase
Training Volume Climbs
Pushing training harder as the stack settles in. Fat loss is already visible. Joints feel genuinely good — credit to BPC-157, TB-500, and GHK-Cu running together.
Recomp Phase
Deep Into the Work
Body composition is shifting noticeably. Energy stays consistent and training quality is high. NAD+ and MOTS-c are making a real difference in endurance and recovery.
Ongoing
Where I'm At Now
Holding the protocol steady. Each compound has settled into its role and the stack as a whole is doing exactly what I built it to do. Bloodwork at the midpoint check came back clean.
Things Worth Knowing
Reconstitute Correctly
Use bacteriostatic water every time. Keep peptides at 2–8°C after mixing. Don't freeze them once reconstituted.
Track Your Protein
Retatrutide suppresses appetite hard. Deliberately track protein to hit 1g per lb of bodyweight. Don't assume you're eating enough just because you feel full.
Get Bloodwork Done
Baseline before starting and check again at the midpoint. Glucose, lipids, liver markers. No exceptions, regardless of how you're feeling.
Inject Site Rotation
Running this many subq compounds means rotating injection sites is non-negotiable. Cycle between abdomen, thigh, and the back of the arm to keep tissue healthy.
GI on Retatrutide
Can cause mild nausea, especially early on or when adjusting dose. Smaller meals and avoiding high-fat foods around injection day helps. It passes quickly.
Hydration & Electrolytes
Running this many compounds in a caloric deficit makes hydration critical. Daily electrolytes make a clear difference in training performance and recovery.
Anabolic Support Stack
Testosterone Propionate
300 mg / week
Masteron Propionate
300 mg / week
Growth Hormone
4 IUs / daily
Ready to start your protocol?
Everything in Devin's ascension stack is available at Natty Vision.
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